WEBVTT
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The topics and opinions express in the following show are
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solely those of the hosts and their guests and not
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those of W FOURCY Radio. It's employees are affiliates. We
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Welcome to to Ask Good Questions Podcasts, broadcasting live every Wednesday,
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six pm Eastern Time on W four CY Radio at
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W fourcy dot com. This week and every week, we
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will reach for a higher purpose in money and life,
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as well as a focus on health and wellness. Now,
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let's join your hosts, but ned up Belle Anderson, as
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together we start with Asking Good Questions.
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Welcome to the Ask Good Questions Podcast. I am your host,
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Benita bell Anderson, and we have a fantastic show today
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that I think you are going to really everybody seems
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to be interested in this talkic topic. We are going
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to be talking about jailp drugs, We are going to
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be talking to a doctor that has a very fantastic
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whole outlook on this, so you are going to want
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to stay tuned and listen in on this. So with that,
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I'd like to invite doctor William Summers to the podcast stage.
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Thank you, Benita, thanks for having me.
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Thank you so much for joining us today. Well let
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me tell you a little bit about him.
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He is.
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You know this, this whole thing with JLP one drugs
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has gone from a diabetes treatment to a cultural phenomenon,
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really and with that fame comes a flood of miss
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scare stories, sales pitches. We are going to get of
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all that today. Doctor William Summers brings four decades of
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medical experience and a clinic owner's front row view to
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a candid discussion about weight loss as a medical issue, right,
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not a matter of willpower. We're going to tackle the
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muscle loss debate. We're going to talk about the side
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effects the new pills. Actually I never do this because
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I usually don't want to say a date, but today
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is July first, twenty twenty six. Medicare has made this
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available and so there's some ramifications around that that we
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are going to talk about so welcome, Dtor Summers.
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Thank you.
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Tell me where you coming from.
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Uh, I'm sorry, I'm from Birmingham, Alabama, And I let
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everybody know I'm double boarded. I say double boring. I'm
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boarded in obg in and obesity medicine and have had
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the privilege of practicing AIN for about fifteen years as
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a major part of my clinical practice.
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Wow awesome. Well for someone who's heard the brand names,
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how could they not? There's all these things on TV,
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isn't there? Yes, So exactly what exactly is that GLP
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one drug and how do they work in the body?
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Well, I think the best place to start for people
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to understand what we're talking about. It was discovered in
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recent years that when anyone is overweight, we can measure
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four neurochemicals and our body that are messed up. And
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when they are messed up and we eat, and we
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all have to eat, and these chemicals are messed up,
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we gain weight unfairly. So the first one a very
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important one. GLP one stands for glikagon like peptide one,
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a small peptide, and this is made in our intestines
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and every time we eat a meal, this peptide goes
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inside our brain and makes us feel satisfied or full,
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the satiety hormone, and it goes outside the brain to
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help regulate blood sugar. Blood sugar regulation is critical to
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normal weight gain. So with the GLP one being messed
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up and that was identified, then this medicine came along
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that will help fix that to actually put that back
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into our body, elevating the GLP one that is low
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and you get full, quicker regulating your blood sugar. And
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this was just a huge breakthrough in the medical science
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for weight gain and obesity management. It came also secondarily
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that another chemical identified called GIP gastro inhibitory peptide made
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in the intestine is really helps regulate blood sugar is
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messed up. So then they have a medicine I just
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call them four buttons are messed up. We have the
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medicine zema glue type known as ozipic we Goobe fixes
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one button. We have the terzeppatide known as Monjoro for
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type two diabetes rename zet Bound fixes two of the buttons,
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and the fantastic drug which will be released fully next year,
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also made by Eli Lilly, will fix three the buttons.
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It's known as ratitude tried. These are all injections and
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they all have pretty much we could talk about one, two,
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or three and they have pretty much the same side
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effect profile. But they are definitely all in the sense
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good for the heart and heart disease and stroke are
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the number one killer in this country. They treat the
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abdominal obesity and two hundred diseases are associated with abdominal obesity.
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So I think we are onto something like the pedicillins
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of weight loss, just getting started with a great future ahead.
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Well, one of the things that somebody said to me,
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not just recently, was, you know, being overweight is a
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side effect of you know, it's like people are we're
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going to be talking about the side effects today, but
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just being overweight is a huge side effect and risk
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to your health in and of itself.
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And almost all circumstances. That is true. There is such
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a there's a clinical entity called the healthy obese patient.
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So I just want to clarify that not everybody with
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obesity has medical issues, and let's put that out there,
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but most of us with obesity, we do have medical issues,
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and it's good to just be educated about that and
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understand what is available, and then choose options individually, lifestyle
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options and even if it goes there to medical options,
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but to have an understanding what we're doing, what we're taking,
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and what to expect.
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So you've you've been practicing for forty years, Yes, how
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did a medication that was originally meant for diabetes become
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a weight loss tool?
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Well, if we it's interesting because it was all developed,
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as you just mentioned, with the beginning of advanced studies
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for type two diabetes and the path of physiology, we
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gain weight, chemicals are messed up, we gain more weight,
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chemicals messed up, and as we go up the weight
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gain ladder, the top of the hill, we have type
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two diabetes. So the po physiology for obesity and type
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two diabetes it's pretty much the same road. So we
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have a drug that will fix that road. But the
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drug gets two names. One drug will get two names
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if well, for a diabetic patient it's called ozipic or
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and for a diabetic patient Manjo road. But for a
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white patient we go or zet bound. So it was
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just by I think incidental or accidental or observational studies
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that hey, when we do everything for diabetes, we're also
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doing the weight loss, and then the sort of the
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parallel path of physiology was recognized, and so those two
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are studied together.
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Well, you know this whole thing with treating obesity, because
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I think a lot of times people have been shamed
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thinking it's just a willpower problem. It's you know, I'm
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I'm just a bad person, I you know, And so
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there's a distinction between it's all your fault and this
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is a medical problem. So does that just think should
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matter to you when you're trying to treat patients.
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This is where I get in my soapbox. My passion
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goes off the chain. This is a disease. Obesity is
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a chronic disease. Just like if you had some type
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of strap throat and problems and we now know, well
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we can use medicines or treatments for that. This is
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no different. And this whole stigma and this and this
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discriminating and shaming people anywhere anywhere for any reason, it's wrong,
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and I just get so frustrated and passionate defense just
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like the understanding the disease. Education to understand the disease
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will help us take the blame and shame which should
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never exist in obesity or anywhere in our culture period.
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Well you originally, I mean, you're an obgun, right, but
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did this I mean, I just want to, you know,
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walk us through. Did you kind of start moving in
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this direction as you I mean you were you know,
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you basically start out with traditional medicine, but this is
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kind of taken over right.
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Well, as you mentioned, I've been had the privilege of
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having a practice for forty years with obg WAN my
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patient population or women of all ages, and we've had
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a lot of medical training and surgical training to get
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to just start a practice. But what we never got
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trained in is what we're talking about right now. And
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when women come in to my practice, from the beginning
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of the get go, they would ask me about their
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weight problems and their weight gain, and it became very
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frustrating because I didn't have any tools in my toolbox,
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and so going in and trying to dive deeper into
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what we had, we had very very limited tools, many
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of which we thought were good and turned out later
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not to be good. So the discovery of now what
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we know the facts about the disease of obesity excites
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me because we can target that like any other disease,
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so that it was just by the patient population and
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the problem that women now and I always will mention this,
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and it's really unfortunately true. Men gain weight and we
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don't like the weight, but women gain weight and don't
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like themselves, and that's misogyny driven. It's wrong. It should
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never be a double standard, but it is real, and
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you can ask men and women this is true. So
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with women with a population affecting their confidence, socialization, sexual responsivity,
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been there with something. So I've always been looking for
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something to help. And now when we had tools that
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really do sort of parallel the path of physiology treating,
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like any of the disease efficacy driven studies, it excites
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me to have something in a toolbox to help a
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patient that comes to me.
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Right, well, let's talk a little bit about some of
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the myths that are out there. Let's talk about what's
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really true here. So what's the single biggest myth that
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you wish you could just cut through right now, get
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rid of it?
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Oh wow, there's so many of these. I think that
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the biggest myth overall is that when people say, well,
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if I use these medicines, then if I stop them,
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I will become a diabetic, and I'm like, oh okay,
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and it's like what you know, we you know, we
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are all sort of on the diabatic hill. Remember that
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an A one C in nineteen sixty four was five
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point nine and you were a type two diabetic. And
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we have all been going up to diabetic hill. And
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so now an A one C six point five is
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the type two diabetic. And we're as we get bigger
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and more belly fat and more insulin resistance and we're
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belly fat. We're just on this snowball getting bigger. So
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people have this something in their head that since the
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medicines are used to treat diabetes, that and the path
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of physiology overlaps are used to treat weight loss. In
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their head they think, well, I just don't want to
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be on these medicines forever. No, you don't have to
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be well if I stop this, am I going to
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be a diabetic? No, you're not going to be a diabetic.
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So that's it's it's I understand where the confusion comes from.
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But all of this, Hey, we're going to prevent diabetes
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with these and losing weight will put you lower on
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the hill, and that yes, if we don't make health
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style changes to maybe keep us in a better place.
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We're all going to be diabetic because fifty fifty percent
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of our population today would be type two diabetes to
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type two diabetic if we use the original five point
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nine A one C, that's considered pre diabetes. Now wow, okay,
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so that's the one that I just want to educate
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to clarify. I get all types of questions about well,
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my hair will fall out, and people read about that,
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and there's sort of a and there is, unfortunately a
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small population of people when they use one of these medicines,
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there's a direct effect on the hair follicle. It's not permanent,
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but it scares them. And then there's an indirect effect
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because the weight loss that occurs, and this you can
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say compared to bariatric surgery and weight loss, the weight
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loss is a stress to our body. We are designed
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physiologically to gain weight. Our body wants to gain weight,
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so lousy waight, we go into like a little mini
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shock in a way affecting hair. But for the most
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most people, we don't need to worry about that, and
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we address that individually as a real problem. When people
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have concerns about it. There have been a host of
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compound medicines in the past, things that should not have
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been on the market eligible for use by patient's research
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grade medicines being given, and desperation salted version of semi
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glue tide, which is not the formula, that is the
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base type peptide that they make. But so a lot
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hit the market fast, and that created a lot of confusion.
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But just and people have a needle aversion, and I
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probably do, but I would say this is, this is,
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this is if I could do an if I can
243
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do it, because you don't it's really you don't feel this.